Wrinkle Shot Medical Serum N, 20g

Product Name: POLA Wrinkle Shot Medical Serum N. Quasi-drug. Allergy tested (does not guarantee allergy-free for all individuals). Contains Pola Orbis Group's proprietary ingredient, Neil One®, the first wrinkle-reducing quasi-drug approved in Japan. It also features a new dynamic delivery formula, allowing the active ingredient Neil One* to penetrate deep into the dermis, improving wrinkles. Use approximately four months for one area and two months for two areas. * Neil One: Trifluoroisopropyloxopropylaminocarbonylpyrrolidinecarbonylmethylpropylaminocarbonylbenzoylaminoacetic acid Na. Launched in 2017 as Japan's first*1 wrinkle-reducing medicated cosmetic, Wrinkle Shot has been enjoyed by approximately 1.75 million*2 consumers. Even after its launch, we have continued our research as a pioneer in wrinkle improvement. By accurately identifying the causes of wrinkles, the active ingredient Neil One*3 penetrates deep into the dermis, improving wrinkles. Causes of Wrinkles Wrinkles are primarily caused by UV rays and facial pressure, which overproduce enzymes (such as neutrophil elastase) that break down dermal components, damaging the skin. How it Improves Wrinkles*4: The active wrinkle-improving ingredient "Nilone" suppresses the activity of neutrophil elastase, inhibiting the breakdown of dermal components in wrinkled areas and supporting the production of dermal components, thereby improving wrinkles. *1 First in Japan: First product approved in July 2016 as a quasi-drug for improving wrinkles. *2 Approximately 1.75 million people: Sales figures from January 2017 to the end of March 2024 (according to POLA). *3 Neilone: ​​Trifluoroisopropyloxopropylaminocarbonylpyrrolidinecarbonylmethylpropylaminocarbonylbenzoylaminoacetic acid Na*4 Wrinkle Improvement: Significance was achieved within the evaluation criteria of the Anti-Wrinkle Product Evaluation Guidelines for Acquiring New Efficacy established by the Japan Cosmetic Science Society. (Quasi-drug)